The Health Sciences Authority (HSA) Singapore has published the first version of the guidelines on the establishment of ingredients’ safety for traditional medicines (TM) and health supplements (HS) in March 2022.
Importers, manufacturers, and wholesale dealers are required to maintain the safety standards of their products. Ingredients listed in Poisons Act (Chapter 234) & Poison Rules, Sale of Drugs Act (Chapter 282) & its Regulations, Misuse of Drugs Act (Chapter 185) & its Regulations, and ASEAN Guiding Principles for Inclusion into or Exclusion from the Negative List of Substances for TM and HS, as well as ingredients derived from humans are not allowed to be included in these products.
The identity of each active ingredient must be known, and scientific information shall be available for review. Reference books and ingredients monographs are examples of literature evidence for the safe use of an active ingredient.
More details can be found in “Guidelines for Establishing the Safety of Ingredients of Traditional Medicines and Health Supplements, March 2022”: https://www.hsa.gov.sg/docs/default-source/hprg-tmhs/chpb-tmhs/tmhs_ing_guidelines.pdf